METHOD OF MYOCARDIAL PERFUSION INITIAL DISTURBANCES AND NON-UNIFORMITY QUANTITATIVE ASSESSMENT ACCORDING TO SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY DATA Russian patent published in 2016 - IPC A61B6/03 

FIELD: medicine.

SUBSTANCE: invention refers to medicine, clinical cardiology and can be used for quantitative assessment of myocardial perfusion initial disturbances and non-uniformity according to data of single photon emission computed tomography (SPECT). At that, perfusion disturbances severity index σ_t and perfusion non-uniformity index σ_nare determined, reflecting whole left ventricular myocardium (LV) perfusion violations. Indices are calculated as perfusion mean-square deviations in segments by formula:

,

where n is number of segments, P are relative perfusion values in segment (in %), M[P] - mathematical expectation for P and M[P] for severity index σ_t - 100 %, and for non-uniformity indexσ_n is relative perfusion in all segments arithmetic mean value (P_av). If values σ_t < 20 and σ_n not exceeding 6.1 myocardial perfusion is considered to be normal. If values σ_t > 20 and σ_n < 6.1 or σ_t > 25 and 6.1 < σ_h < 10 conclusion is made on perfusion non-uniformity with perfusion reduction multiple sections. If values σ_t < 25 and 6.1 < σ_h < 10 or 20 < σ_t < 25 and σ_h > 10 conclusion is made on perfusion non-uniformity with perfusion reduction single section. If values σ_t > 25 and σ_h > 10 conclusion is made on reliable perfusion defects presence.

EFFECT: method provides high sensitivity, accuracy of quantitative assessment of myocardial perfusion initial disturbances and non-uniformity.

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