TOPICAL LOCALIZED ISOXAZOLINE FORMULATION COMPRISING GLYCOFUROL Russian patent published in 2016 - IPC A61P33/00 A01N65/00 A61K31/42 

FIELD: veterinary science.

SUBSTANCE: group of inventions refers to veterinary science, namely to a method of treating and preventing parasite infestation in animals by compositions for external and local application. For this purpose, the composition containing 1-50 % wt/vol. of an isoxazoline compound (I) and veterinary acceptable liquid carrier vehicle containing 15-20 % wt/vol. of glycofurol and 5-95 % wt/vol. of auxiliary solvents mixture, such as dimethylacetamide, acetone and N,N-diethyl-3-methylbenzamide. Compound I is a 4-[5-(3,5-dichlorophenyl)-5-trifluoromethyl-4,5-dihydroisoxazol-3-yl]-2-methyl-N-[(2,2,2-trifluoro-ethylcarbamoyl)-methyl]benzamide. Composition can also contain an effective amount of macrocyclic lactone compound.

EFFECT: group of inventions provides a cosmetically acceptable formulations for external and local application effective for a long period of time in treating ectoparasite infestation in animals.

8 cl, 3 tbl, 3 dwg, 4 ex