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(19)

RU

(11)

2 611 187

(13)

C2

(51)

IPC

C12N15/113(2010-01-01)

A61K31/7088(2006-01-01)

A61K48/00(2006-01-01)

(21) (22)

Application

2012125364, 2011-01-04

(24)

Start date

2011-01-04

(22)

Actual filing date

2011-01-04

(45)

Published

2017-02-21

(72)

Inventor

Kollard DzhozefKhorkova Sherman Olga

(73)

Holder

Kurna, Ink.

TREATMENT DISEASES, ASSOCIATED WITH INTERFERON-REGULATORY FACTOR 8 (IRF8), BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO IRF8 Russian patent published in 2017 - IPC C12N15/113 A61K31/7088 A61K48/00 

Abstract RU 2611187 C2

FIELD: chemistry.

SUBSTANCE: present invention relates to antisense oligonucleotides, modulating expression and/or function of interferon-regulatory factor 8 (IRF8), in particular, by targeted interaction with natural antisense polynucleotides of interferon regulatory factor 8 (IRF8).

EFFECT: present invention also relates to identification of such antisense oligonucleotides and use thereof in treating diseases and disorders associated with expression of IRF8.

32 cl, 1 dwg

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RU 2 611 187 C2

Authors

Kollard Dzhozef

Khorkova Sherman Olga

Dates

2017-02-21—Published

2011-01-04—Filed

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