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2 614 264

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IPC

C12N15/22(2006-01-01)

C12N15/70(2006-01-01)

C12N1/21(2006-01-01)

C12R1/19(2006-01-01)

(21) (22)

Application

2015123831, 2015-06-19

(24)

Start date

2015-06-19

(22)

Actual filing date

2015-06-19

(45)

Published

2017-03-24

(72)

Inventor

Martynov Aleksandr IgorevichGasanov Vagif Ali OglyShevale Aleksandr FedorovichKhaitov Rakhim Musaevich

(73)

Holder

Federalnoe Gosudarstvennoe Byudzhetnoe Uchrezhdenie Nauchnyj Tsentr Institut Immunologii" Federalnogo Mediko-Biologicheskogo Agentstva Rossii

OPTIMIZED RECOMBINANT PROTEIN ENCODING GENE - HUMAN INTERFERON BETA ANALOG Russian patent published in 2017 - IPC C12N15/22 C12N15/70 C12N1/21 C12R1/19

Abstract RU 2614264 C2

FIELD: biotechnology.

SUBSTANCE: nucleotide sequence encoding a recombinant protein - interferon beta analog, optimized for expression in E. coli cells. E. coli BL-30-B cell, intended for interferon beta recombinant protein production is obtained by transformation of E. coli BL (DE3) cells by rET30a plasmid containing the said nucleic acid. E. coli BL-32-B cell, intended for interferon beta recombinant protein production is obtained by transformation of E. coli BL (DE3) cells by rET32a plasmid containing the said nucleic acid.

EFFECT: invention provides a recombinant protein.

3 cl, 5 dwg, 9 tbl, 9 ex

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RU 2 614 264 C2

Authors

Martynov Aleksandr Igorevich

Gasanov Vagif Ali Ogly

Shevale Aleksandr Fedorovich

Khaitov Rakhim Musaevich

Dates

2017-03-24—Published

2015-06-19—Filed