FIELD: medicine.
SUBSTANCE: for melanoma B16 lymphatic and hematogenous metastasis simulation, nonlinear white rats are used. 2 weeks after spleen removal suspension of murine melnoma B16 tumour cells in saline is implanted under the anterior abdominal wall skin, in a volume of 0.1 ml and at dilution of 1:10. Six months after inoculation, lymphatic and hematogenous melanoma distribution pathway with morphologically confirmed metastatic lesions of internal organs is recorded.
EFFECT: method ensures simulation accuracy, is economical and simple to implement.
6 dwg
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR ENHANCING THE GROWTH OF B16/F10 MELANOMA VERSUS THE GROWTH OF B16/F10 MELANOMA WITH SELF-GRAFTING AND SLOWING THE GROWTH OF LLC (LEWIS CARCINOMA) VERSUS THE GROWTH OF LLC WITH SELF-GRAFTING IN CASE OF MULTIPLE PRIMARY MALIGNANT TUMORS AGAINST THE BACKGROUND OF PRIMARY IMMUNODEFICIENCY | 2021 |
|
RU2759487C1 |
| METHOD OF MODIFYING THE DEVELOPMENT OF ADENOCARCINOMA EXPERIMENTALLY | 2020 |
|
RU2743960C1 |
| METHOD FOR SIMULATING LIVER METASTASES EXPERIMENTALLY | 2013 |
|
RU2538243C1 |
| METHOD OF THE MELANOMA B MALIGNANT GROWTH IN MICE MODIFICATION WITH CHRONIC PAIN | 2017 |
|
RU2650587C1 |
| A METHOD FOR MODELING THE PRIMARY MULTIPLE GROWTH OF MALIGNANT TUMORS WITH THE SUPPRESSION OF ONE TUMOR BY ANOTHER IN THE CONDITIONS OF PRIMARY IMMUNODEFICIENCY | 2021 |
|
RU2750127C1 |
| METHOD OF HUMAN OVARIAN CANCER TUMOR FRAGMENT TRANSPLANTATION INTO OVARY OF IMMUNE-DEFICIENT FEMALE MOUSE | 2020 |
|
RU2740443C1 |
| METHOD OF THE MELANOMA TUMOR NODES FORMATION IN THE BODY OF EXPERIMENTAL ANIMALS | 2022 |
|
RU2796892C1 |
| METHOD FOR CREATING POLYNEOPLASIA WITH STIMULATION OF TUMOR GROWTH IN CONDITIONS OF PRIMARY IMMUNODEFICIENCY IN EXPERIMENT | 2021 |
|
RU2751930C1 |
| STRAIN OF RAT RABDOMYOSARCOME RA-22 CELLS, USED FOR FEATURE TUMORS DETECTION, RESISTANT TO HYPERTHERMIA TREATMENT | 0 |
|
SU1751201A1 |
| METHOD FOR EXPERIMENTAL BIOTHERAPY OF B16/F10 MELANOMA | 2022 |
|
RU2779698C1 |
