FIELD: experimental oncology.
SUBSTANCE: invention can be used to form melanoma tumor nodes in experimental animals. Mitochondria isolated from B16/F10 melanoma are transplanted intramuscularly and Balb/c Nude intraperitoneally into male mice of the C57BL/6 line intramuscularly and Balb/c Nude at a ratio of 5.2 mg of protein per 1 animal in 0.4 ml of saline.
EFFECT: invention makes it possible to study the pathogenesis of malignant growth under the influence of transplantation of mitochondria isolated from melanoma, and the mechanism of mitochondrial action causing the development of melanoma tumor foci.
1 cl, 15 dwg
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