A METHOD FOR MODELING THE PRIMARY MULTIPLE GROWTH OF MALIGNANT TUMORS WITH THE SUPPRESSION OF ONE TUMOR BY ANOTHER IN THE CONDITIONS OF PRIMARY IMMUNODEFICIENCY Russian patent published in 2021 - IPC G09B23/28 

Abstract RU 2750127 C1

FIELD: medicine, experimental oncology in particular.

SUBSTANCE: invention relates to oncology, namely to experimental oncology, and can be used to study the pathogenesis of the primary multiple neoplastic process in an experiment. A method for modeling the primary multiple growth of malignant tumors with the suppression of one tumor by another in conditions of primary immunodeficiency is that female BALB/c Nude mice are subcutaneously injected under the scapula on the left with a suspension of mouse melanoma B16/F10 tumor cells in 0.5 ml of saline solution in a 1:20 dilution, while 0.5 million Guerin rat carcinoma tumor cells in 0.5 ml of saline solution are injected under the scapula on the right.

EFFECT: invention provides the creation of a model of primary multiple malignant growth by subcutaneous grafting of melanoma B16/F10 and Guerin's carcinoma to BALB/c Nude mice.

1 cl, 2 dwg, 1 tbl

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Authors

Frantsiiants Elena Mikhailovna

Kaplieva Irina Viktorovna

Shikhliarova Alla Ivanovna

Trepitaki Lidiia Konstantinovna

Surikova Ekaterina Igorevna

Bandovkina Valeriia Akhtiamovna

Neskubina Irina Valerevna

Shumarin Konstantin Aleksandrovich

Kotieva Inga Movlievna

Dates

2021-06-22Published

2021-02-02Filed