PREDICTING LIKELIHOOD OF ONSET OF CLINICAL PREGNANCY OF WOMEN WITH BMI 28,5 AND ABOVE IN VITROFERTILIZATION PROGRAM BASED ON ESTIMATES OF WAIST CIRCUMFERENCE AND CHANGES IN SHARE OF PERIPHERAL BLOOD MONOCLEAR WITH HIGHLY MITOCHONDRIA AS A RESULT OF SUPEROVULATION Russian patent published in 2017 - IPC G01N33/48 

FIELD: medicine.

SUBSTANCE: method is based on an assessment of the percentage of peripheral blood mononuclear cells (PMC) with highly mitochondria before and after superovulation and measuring waist circumference (WC). The probability of a clinical pregnancy is calculated according to the formula: p = exp (logit)/(1+exp (logit)), where logit = -5.11 (0.048⋅OT) - (0.124⋅Δ PMC), where p - the probability of clinical pregnancy, Δ PMC - the percentage of peripheral blood mononuclear cells with HIGHLY mitochondria before and after the stimulation end. For values of p greater than 0.5 predict the probability of clinical pregnancy.

EFFECT: use of this method allows on the basis of measurements of the above parameters during the treatment in the IVF program in the case of predicting a low probability of a positive outcome of treatment to change tactics and to recommend the abolition of the transfer of embryos in this cycle, with subsequent cryopreservation and transfer into the uterus after normalization at this woman's body weight.

1 tbl, 3 ex