FIELD: medicine, pharmacy.
SUBSTANCE: invention refers to ivabradine hydrochloride form IV with powder diffraction containing the following peaks expressed in 2 theta (±0.2) degrees: 8.74, 15.55, 17.17, 19.89 and 24.29, at that, the X-ray diffraction was measured using CuK-radiationα, as well as to pharmaceutical compositions based thereon, to methods for its preparation and application as a therapeutically active ingredient.
EFFECT: invention provides a new thermodynamically stable crystalline form of ivabradine hydrochloride with constant physical properties.
31 cl, 4 dwg, 2 tbl, 32 ex
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