BIOACTIVE COMPOSING MATERIAL FOR REPLACEMENT OF BONE DEFECTS AND METHOD FOR PRODUCING THEREOF Russian patent published in 2019 - IPC A61L27/12 A61F2/28 

FIELD: medicine; pharmaceuticals.

SUBSTANCE: invention relates to the field of biologically active pharmaceutical and medical materials with high mechanical strength, such materials can be used in orthopedic dentistry and surgery for recovery and treatment of bone tissue, as well as a carrier of biologically active substances. Disclosed is a method of producing a bioactive composite material for bone defect replacement, comprising mixing a hydroxyapatite and calcium fluoride, taken in a weight ratio of 5.25–6.14:1, respectively, mixed until complete homogenisation, tableted at pressure of 200–300 MPa and annealed at temperature of 950–1050 °C for 1–1.5 hours.

EFFECT: obtained composite bioactive material (Ca₁₀(PO₄)₆(OH)₂-CaF₂, having an herringbone crystalline structure and high hardness, can be used in orthopedic dentistry and surgery for bone tissue repair and treatment.

1 cl, 1 tbl, 2 ex