METHOD OF PREDICTING RECURRENT SOFT TISSUE SARCOMAS Russian patent published in 2017 - IPC G01N33/53 

Abstract RU 2625035 C1

FIELD: medicine.

SUBSTANCE: to determine the occurrence of recurrence with flow cytometry, the percentage of T-regs(CD3+CD4+CD25+CD127dim) of lymphocytes from CD3+CD4+cells in homogenates of tumor tissue samples and in the line of resection after surgical removal of the tumor is determined. If this value is higher than 11.1% in tumor tissue and 7.1% in the tissue of the resection line, the recurrence of the sarcoma is predicted.

EFFECT: use of this method allows predicting the occurrence of relapse in the treatment of soft tissue sarcomas by determining the percentage of lymphocyte subpopulation, since this population of cells influences the development of antitumor immune responses.

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RU 2 625 035 C1

Authors

Kit Oleg Ivanovich

Zlatnik Elena Yurevna

Novikova Inna Arnoldovna

Selyutina Olesya Nikolaevna

Aliev Timur Arsenovich

Andrejko Elena Anatolevna

Nepomnyashchaya Evgeniya Markovna

Dates

2017-07-11Published

2016-09-06Filed