METHOD FOR INDIVIDUAL PREDICTION OF PROGRESSION OF SQUAMOUS CELL ESOPHAGUS CANCER II-III STAGE AFTER SURGICAL TREATMENT Russian patent published in 2020 - IPC G01N33/48 G01N33/49 

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to oncology, and can be used in treating esophageal cancer to predict the progression of postoperative progression. A method for individual prediction of the progression of squamous cell esophagus cancer II-III stage after surgical treatment, involving tumor tissue sampling during the operation, homogenization and determination by flow cytofluorometry of lymphocyte composition with immunophenotype CD45+, CD3+, CD19+, CD3+CD4+, CD3+CD8+, CD16/56+ and CD3+CD4+CD127dim (T-reg), then calculating indices: no risk of progression for 2 or more postoperative years – F₀, disease progression for 6–12 months after operation – F_6-12, disease progression for 12–24 months after operation – F_12-24 by formulas, obtained values of parameters F₀, F_6-12, F_12-24 comparing to each other and by the maximum value F predicting the duration of esophageal cancer progression after surgical treatment.

EFFECT: method enables more accurate prediction of progression of esophageal cancer II-III stage, including delineation of its progression and individualization.

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