FIELD: medicine.
SUBSTANCE: method includes analysis of the transcriptome of the ovarian endometriosis focus endometrioid tissue by a TIMP1 gene expression study, when the TIMP1 gene expression exceeds 0.5 p.u. relative to the gene, the patients are assigned to the group with a glandular-cystic type of ovarian endometriosis, if it is less than or equal to 0.5 p.u. - to a group with a cystic version of ovarian endometriosis. The proposed marker has specificity - 73%, sensitivity - 83%, AUC=0.82.
EFFECT: increased effectiveness of diagnosis, allows a personalized approach to the treatment of patients with ovarian endometriosis.
4 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR EARLY DIAGNOSIS OF NEOPLASTIC TRANSFORMATION OF ENDOMETRIOID OVARIAN CYSTS | 2020 |
|
RU2730952C1 |
| METHOD FOR PREDICTION OF RECURRENT ENDOMETRIOID OVARIAN CYSTS | 2018 |
|
RU2694882C1 |
| METHOD OF DETERMINING RISK OF RECURRENCE OF ENDOMETRIOID OVARIAN CYSTS AFTER SURGICAL TREATMENT | 2023 |
|
RU2811890C1 |
| MINIMALLY INVASIVE METHOD FOR DIAGNOSIS OF HIGH-GRADE SEROUS OVARIAN ADENOCARCINOMA BASED ON COPY INDEX OF SULT1E1, CYP1B1, AND ESR1 GENES | 2021 |
|
RU2750472C1 |
| METHOD FOR DIFFERENTIAL DIAGNOSIS OF OVARIAN CANCER, OVARIAN CYSTIC GROWTHS AND UTERINE CANCER | 2024 |
|
RU2836527C1 |
| METHOD FOR PREDICTING RECURRENCE OF ENDOMETRIOID OVARIAN CYSTS AFTER SURGICAL TREATMENT | 2021 |
|
RU2757236C1 |
| METHOD FOR DIAGNOSTICS OF MINOR FORMS OF ENDOMETRIOSIS | 2020 |
|
RU2749290C1 |
| METHOD FOR DIFFERENTIAL DIAGNOSIS OF BENIGN AND MALIGNANT NEOPLASMS OF OVARIES | 2018 |
|
RU2686180C1 |
| METHOD FOR PREDICTING THE RECURRENCE OF ENDOMETRIAL CYSTS AFTER SURGICAL TREATMENT BY MEANS OF IMMUNOHISTOCHEMICAL MARKERS | 2017 |
|
RU2681219C1 |
| PREDICTION OF DEVELOPMENT OF COMMON FORMS OF INFILTRATIVE ENDOMETRIOSISS BASED ON EVALUATION OF CD15 EXPRESSION IN ENDOMETRIC BIOPSY MATERIALS | 2016 |
|
RU2634263C1 |
