FIELD: pharmacology.
SUBSTANCE: method includes separating the cleaned extracellular matrix layers from the cleaned, extruding the layers, fractionating the powder and suspending the selected fraction of the purified extracellular matrix particles in a liquid medium by alternating the mixing and dispersing cycles of the particles in a liquid medium with a predominant mixing time at a temperature that does not induce denaturation of the collagen, and degassing the resulting particle suspension.
EFFECT: method of the invention provides for the preparation of a suspension form of a decellularized extracellular matrix with an adjustable size of its structural components, the use of which allows for the injection of injections into the desired region without incision and easily filling the open wound defect of various tissues.
12 cl, 6 dwg, 1 tbl
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