METHOD FOR PREDICTION OF ECOLI TRANSLOCATION FROM INTERSTINE IN CASE OF NON-CULTURED TYPE OF INFECTIOUS PROCESS IN EXPERIMENT WITH RABBITS Russian patent published in 2017 - IPC G09B23/28 

Abstract RU 2628063 C1

FIELD: biotechnology.

SUBSTANCE: method involves infection of rabbits using a suspension of non-cultivated P. aeruginosa and S. aureus bacteria in concentrations of 105-106 microbial cells per 1 ml on a physiological solution of sodium chloride, which is administered subcutaneously. ALT and urea are examined in the blood serum on days 1-2 and 4-5. With ALT equal to 53.0-63.0 u/l on days 1-2, and 57.0-69.0 u/l on days 4-5, and urea concentration index equal to 4.6-6.6 u/l on days 1-2, and 1.3-1.9 u/l on day 4-5, development of E. coli translocation from the intestine to the internal organs of the animal is predicted.

EFFECT: results allow to extrapolate the obtained data to humans in order to improve diagnosis and treatment of patients in case infectious processes caused by noncultured bacteria.

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RU 2 628 063 C1

Authors

Sakharov Sergej Pavlovich

Kozlov Leonid Borisovich

Kozlov Oleg Evgenevich

Dates

2017-08-14Published

2016-09-22Filed