NEW FUCOSYLTRANSFERASES AND APPLICATIONS THEREOF Russian patent published in 2017 - IPC C12N9/10 C12P19/18 

FIELD: biotechnology.

SUBSTANCE: bacterial host cell is provided comprising a sequence consisting of a polynucleotide encoding a polypeptide with alpha-1,2-fucosyltransferase activity (SEQ ID NO: 1) to produce 2'-fucosyllactose. Also methods for 2'-fucosyllactose production using the said polypeptide with alpha-1,2-fucosyltransferase activity, a donor substrate containing a fucose residue and an acceptor substrate comprising or consisting of lactose.

EFFECT: group of inventions allows to facilitate production of fucosylated oligosaccharides of human milk, making it more efficient and economical due to the possibility of lactose application as a substrate for alpha-1,2-fucosyltransferase.

9 cl, 13 dwg, 3 tbl, 1 ex