FIELD: biotechnology.
SUBSTANCE: method for identification of pathogens of nosocomial opportunistic infections and markers of their resistance to beta-lactam antibiotics and glycopeptides in women of reproductive age and newborns includes real-time PCR and determination of the following parameters: presence of human genomic DNA, total bacterial mass, presence of UPM DNA belonging to eight taxa (family: Enterobacteriaceae, genera: Staphylococcus, Enterococcus, Acinetobacter, a complex of species: Burkholderia cepacia, species: Staphylococcus aureus, Pseudomonas aeruginosa, Stenotrophomonas Maltophilia), and 15 markers of microorganism resistance to antibiotics: mecA, vanA, vanB, blaTEM, blaSHV, blaCTX-M blaOXA23-like genes, blaOXA40-like genes, blaOXA48-like genes, blaOXA51-like genes, blaOXA58-like genes, BlaNDM, blaVIM, blaKPC, blaIMP, and the best antibacterial drugs are selected according to the received data.
EFFECT: expansion of the compound application field.
5 tbl, 3 ex
| Title | Year | Author | Number |
|---|---|---|---|
| AGENT FOR THE TREATMENT OF INFECTIONS CAUSED BY MULTI-RESISTANT BACTERIA, INCLUDING THOSE PRODUCING CARBAPENEMASE | 2022 |
|
RU2793587C1 |
| METHOD FOR IDENTIFICATION AND EVALUATIION OF OPPORTUNISTIC INFECTIONS AGENTS PATHOGENICITY LEVEL IN WOMEN OF REPRODUCTIVE AGE AND NEWBORN CHILDREN FOR PREDICTION OF COURSE AND DEVELOPMENT OF INFECTIOUS DISEASES COMPLICATIONS | 2016 |
|
RU2638453C1 |
| METHOD FOR PREVENTION OF HEALTHCARE-ASSOCIATED INFECTIONS IN PATIENTS IN CHRONIC CRITICAL CONDITION | 2023 |
|
RU2818910C1 |
| KLEBSIELLA PNEUMONIAE BACTERIAL STRAIN USED AS A TEST CULTURE FOR THE DETECTION OF THE NDM GENE BY POLYMERASE CHAIN REACTION FOR ACCURATE DIAGNOSIS AND PRESCRIPTION OF ANTIBACTERIAL THERAPY FOR KLEBSIELLA INFECTIONS | 2022 |
|
RU2797025C1 |
| SYNTHETIC OLIGONUCLEOTIDE PRIMERS FOR ACINETOBACTER BACTERIA STRAINS AND INSOLES IDENTIFICATION AND DETERMINATION OF RESISTANCE TO BETA-LACTAM ANTIBIOTICS AND THE METHOD OF THEIR USE | 2016 |
|
RU2646107C1 |
| PLASMID VECTOR pESB FOR ASSESSING THE RESISTANCE OF NEISSERIA GONORRHOEAE TO BETA-LACTAM ANTIBIOTICS AND METHOD FOR CONSTRUCTION THEREOF | 2021 |
|
RU2787047C1 |
| METHOD FOR IDENTIFYING MUTATIONS IN THE GENE OF PENICILLIN-BINDING PROTEIN 2 PENA NEISSERIA GONORRHOEAE, LEADING TO RESISTANCE TO BETA-LACTAM ANTIBIOTICS, ON BIOLOGICAL MICROCHIPS | 2020 |
|
RU2741099C1 |
| METHOD FOR RAPID ANALYSIS OF URINE ON GENES OF BETA-LACTAM RESISTANCE OF UROPATHOGENIC ENTEROBACTERIA IN PREGNANT WOMEN WITH PYELONEPHRITIS | 2020 |
|
RU2738854C1 |
| MULTIRESISTANT STRAIN OF BACTERIA ACINETOBACTER BAUMANNII FOR STANDARDIZATION OF EFFICIENCY EVALUATION OF DEVELOPED ANTIMICROBIAL PREPARATIONS AND DISINFECTANTS | 2019 |
|
RU2711922C1 |
| OLIGONUCLEOTIDE BIOCHIP FOR IDENTIFICATION OF GENETIC DETERMINANT OF NEISSERIA GONORRHOEAE RESISTANCE TO ANTIMICROBIAL PREPARATIONS, SET OF OLIGONUCLEOTIDES USED FOR IMMOBILISATION ON BIOCHIP | 2016 |
|
RU2636457C2 |
