FIELD: biotechnologies.
SUBSTANCE: invention relates to the biotechnology. Method comprises providing a biological microchip with immobilized oligonucleotide probes, multiplex amplification of penA fragments, hybridisation of amplified fluorescent-labeled products on a biochip, recording and interpretation of hybridisation results.
EFFECT: what is described is a method for identifying mutations in the gene penicillin-binding protein 2 penA of the gonorrhea Neisseria gonorrhoeae leading to resistance to beta-lactam antibiotics (penicillins, cephalosporins).
5 cl, 2 ex, 3 tbl, 6 dwg
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