FIELD: pharmacology.
SUBSTANCE: patient's blood plasma obtained using the standard cascade plasmapheresis method is sequentially treated with a solution of the maleimide derived colouring agent sulfo-Cyanine5 and N-(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)thiolactone homocysteine in dimethylsulfoxide with incubation at 37°C for 3.5 and 17 hours respectively, the low molecular weight components of the reaction mixture are separated and the purified high molecular weight fraction is dried and stored until use at -20°C.
EFFECT: higher quality of the end product.
4 cl, 1 dwg, 2 ex
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