VACCINATION BY RECOMBINANT YEAST WITH THE FORMATION OF PROTECTIVE HUMORAL IMMUNE RESPONSE AGAINST SPECIFIED ANTIGENS Russian patent published in 2017 - IPC C12N15/81 A61K39/02 A61K39/12 G01N33/569 

Abstract RU 2630620 C2

FIELD: biotechnology.

SUBSTANCE: recombinant yeast of the strain Kluyveromyces lactis DSM 25405, Kluyveromyces lactis DSM 25406 or Kluyveromyces lactis DSM 25407, which carry the gene for VP2 antigen of the infectious bursitis virus (IBDV), integrated into the yeast genome and providing the expression of the VP2 antigen of IBDV as a foreign protein. A method of subcutaneous vaccination with whole yeast cells of these recombinant yeasts is presented.

EFFECT: group of inventions makes it possible to make the method of subcutaneous vaccination more economical, provides effective protection in viral infections as a result of subcutaneous vaccination using much smaller amounts of yeast.

17 cl, 13 dwg, 1 tbl, 9 ex

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RU 2 630 620 C2

Authors

Brojnig Karin

Berens Sven-Erik

Dates

2017-09-11Published

2012-12-12Filed