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2 634 395

(13)

(51)

IPC

C12N15/86(2006-01-01)

A61K48/00(2006-01-01)

(21) (22)

Application

2015151558, 2015-12-01

(24)

Start date

2015-12-01

(22)

Actual filing date

2015-12-01

(45)

Published

2017-10-26

(72)

Inventor

Orishchenko Konstantin EvgenevichMazunin Ilya Olegovich

(73)

Holder

Federalnoe Gosudarstvennoe Avtonomnoe Obrazovatelnoe Uchrezhdenie Vysshego Professionalnogo Obrazovaniya Federalnyj Universitet Imeni Immanuila Kanta" Im. I. Kanta)

GENETIC CONSTRUCT BASED ON CRISPR/Cas9 GENOME SYSTEM EDITING, CODING Cas9 NUCLEASE, SPECIFICALLY IMPORTED IN HUMAN CELLS MITOCHONDRIA Russian patent published in 2017 - IPC C12N15/86 A61K48/00

Abstract RU 2634395 C1

FIELD: biotechnology.

SUBSTANCE: genetic construct of pMitoCas9 with SEQ ID NO:1 based on the CRISPR/Cas9 genome editing system is obtained, which encodes the cas9 nuclease, specifically imported into human mitochondria.

EFFECT: invention provides efficient synthesis of modified Cas9 nuclease in human cells.

2 dwg

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RU 2 634 395 C1

Authors

Orishchenko Konstantin Evgenevich

Mazunin Ilya Olegovich

Dates

2017-10-26—Published

2015-12-01—Filed