FIELD: medicine.
SUBSTANCE: medical instrument comprises a magnetic resonance imaging system for obtaining magnetic resonance thermometry data from a subject, a high-intensity focused ultrasound system comprising an ultrasound transducer with an electronically-controlled focus which includes a mechanical ultrasonic transducer positioning system, wherein the electronically-controlled focus is implemented with the possibility of focus adjustment within the focus area, and the location of the focus area depends on the position of the ultrasound transducer, a memory for storing machine executable instructions, a processor for managing the medical instrument, causing to obtain of the target area describing space within the subject. The target area is larger than the focus area, dividing the target area into a plurality of subareas, each of the plurality of subareas has a transducer position, when the transducer is in the transducer position, the focus area comprises a subarea, determining a sequence for moving the transducer position to each of the plurality of subareas, determining a selected subarea selected from the plurality of subareas using the sequence, each of the subareas is divided into regions, wherein performing the instructions causes the processor to maintain the target temperature in the target area for a predetermined period of time by repeatedly controlling by the mechanical positioning system to move the transducer to the transducer position of the selected subarea; obtaining magnetic resonance thermometry data, wherein the magnetic resonance thermometry data describe voxel temperature in the subarea, determining the temperature capability chart describing the temperature in each of the voxels using the magnetic resonance thermometry data, heating the subarea independently to the target temperature by controlling the electronically-controlled focus using the algorithm of temperature feedback, which uses the temperature capability chart, changing the selected subarea using the sequence. The computer-readable medium ensures execution of instructions for controlling the medical instrument by the processor.
EFFECT: increase in the volume of continuous hyperthermal treatment area for a long period of time.
14 cl, 8 dwg, 1 tbl
