FIELD: chemistry.
SUBSTANCE: method for producing amorphous calcium carbonate (ACC) comprises combining an aqueous solution containing a soluble calcium salt and the first stabilizing agent with an aqueous solution containing a soluble carbonate to form an ACC suspension. Further, a water miscible organic solvent and a solution containing the second stabilizing agent are added simultaneously or sequentially in any order. The second stabilizing agent and the organic solvent are brought into contact with the ACC suspension within about 2 minutes after its formation to produce a stabilized ACC suspension. The first and the second stabilizing agents are the same or different. The total amount of the stabilizing agent is up to about 12 wt % of the stabilized ACC suspension weight. The organic solvent miscible with water is, at least, 5 wt % of the stabilized ACC suspension weight.
EFFECT: invention allows to increase the stability of amorphous calcium carbonate, which is in the form of a suspension in the aqueous phase or in the form of a powder.
25 cl, 4 dwg, 6 ex
| Title |
Year |
Author |
Number |
| STABILIZED AMORPHOUS CALCIUM CARBONATE FOR THE TREATMENT OF MUSCULAR DYSTROPHY |
2017 |
- Ben Josef
- Shakhar Abrakham
- Arav Amir
|
RU2757419C2 |
| STABILIZED AMORPHOUS CALCIUM CARBONATE FOR USE AS ADDITIVE FOR CELLULAR CULTURAL MEDIA |
2017 |
- Ben, Josef
- Shakhar, Abrakham
- Arav, Amir
|
RU2782476C2 |
| AMORPHOUS CALCIUM CARBONATE COMPOSITIONS FOR INHALATION, SUBLINGUAL OR TRANSBUCKAL ADMINISTRATION |
2016 |
|
RU2748976C2 |
| NON-AQUEOUS LIQUID AND SEMI-SOLID COMPOSITIONS OF AMORPHOUS CALCIUM CARBONATE |
2015 |
- Blum Jigal
- Ben Iosef
- Khershkovits Sharon
|
RU2740453C2 |
| AMORPHOUS CALCIUM CARBONATE, STABILIZED WITH POLYPHOSPHATES OR BISPHOSPHONATES |
2016 |
- Ben Josef
- Blum Igal Dov
- Moshe Khagaj
- Ashkenazi Ben
|
RU2739563C2 |
| HIGH STABILITY PHARMACEUTICAL COMPOSITIONS |
2007 |
- Li Jukhua
- Chien Bendzhamin
|
RU2427383C2 |
| MULTI-PURPOSE ENZYME DETERGENT AND METHODS OF STABILIZING APPLICABLE SOLUTION |
2014 |
- Chan Uendi
- Stoks Dzhennifer
- Dzhensen Lindl
- Silvernejl Karter M.
- Everson Terrens P.
- Legatt Grejg
- Ortmann Natan Richard
- Khemmel Devon Bo
|
RU2642077C2 |
| PHARMACEUTICAL COMPOSITIONS WITH A SELECTED DURATION OF RELEASE |
2017 |
- Li, Yukhua
- Guarino, Endryu
|
RU2756514C1 |
| ENCAPSULATED COMPOSITIONS OF AMORPHOUS CALCIUM CARBONATE |
2015 |
- Abo Rizik Ali
- Khershkovits Sharon
- Ben Iosef
- Blum Jigal
|
RU2694962C2 |
| STABILIZED, SOLID, BLOCK FERMENTED DETERGENT COMPOSITION WITH LOW FOAM FORMATION, METHOD OF CLEANING AND DISINFECTING UNIT FOR TREATING FOOD PROTEIN- CONTAINING FOODSTUFFS, STABILIZED, FERMENTED DETERGENT COMPOSITION IN PARTICLE FORM |
1995 |
- Ouks Tomas R.
- Vik Kristin K.
- Kordz Brjus R.
- Bull Sandra L.
- Rikhter Frensis L.
|
RU2161645C2 |
