FIELD: medicine.
SUBSTANCE: method for preoperative evaluation of the risk of disease progression after radiofrequency thermal ablation of colorectal cancer hepatic metastases in case of cytoreductive surgery is proposed. The level of cancer-embryonic antigen, the presence of mutations in the KRAS gene and the index of metastatic liver damage are determined. The probability of disease progression is calculated by the formula. At P value of less than or equal to 0.37, a low risk of disease progression is determined, and at a value greater than 0.37, a high risk is determined.
EFFECT: invention provides a preoperative evaluation of the risk of disease progression during the first year and can be used in oncology units to determine the tactics of treating patients diagnosed with stage IV colorectal cancer with synchronous multiple bilobar metastases to the liver.
6 tbl, 2 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD OF FINDING INDICATIONS FOR RADIO-FREQUENCY THERMOABILITY IN SYNCHRONOUS MULTIPLE BILOBAR METOSTASES OF COLORECTAL CANCER IN THE LIVER | 2017 |
|
RU2641973C1 |
| METHOD FOR PREDICTION OF RISK OF DEVELOPING PROGRESSION OF DISEASE FOLLOWING RADIOFREQUENCY THERMOABLATION OF HEPATIC METASTASES FROM COLORECTAL CANCER | 2013 |
|
RU2523138C1 |
| METHOD FOR PREDICTING METASTASIS IN COLON CANCER | 2015 |
|
RU2613142C1 |
| METHOD FOR COMBINED TREATMENT OF METASTATIC COLORECTAL CANCER IN PATIENTS WITH RESECTABLE LIVER METASTASES IN ABSENCE OF MUTATIONS IN KRAS GENES | 2023 |
|
RU2819653C1 |
| METHOD OF THE COMBINED TREATMENT OF METASTATIC COLORECTAL CANCER IN PATIENTS WITH RESECTABLE LIVER METASTASES IN THE PRESENCE OF MUTATIONS IN THE KRAS GENES | 2023 |
|
RU2797847C1 |
| METHOD FOR PREDICTING THE ONCOLOGICAL EFFECTIVENESS OF CYTOREDUCTIVE OPERATIONS IN PATIENTS WITH STAGE IV COLON CANCER WITH UNRESECTABLE LIVER METASTASES | 2021 |
|
RU2764372C1 |
| METHOD FOR PREDICTION OF OVERALL SURVIVAL IN PATIENTS SUFFERING FROM LIVER METASTASES OF COLORECTAL CANCER FOLLOWING HEPATIC RESECTION | 2013 |
|
RU2530610C1 |
| METHOD OF PREDICTING RELAPSE-FREE SURVIVAL OF PATIENTS WITH COLORECTAL CANCER METASTASES IN LIVER AFTER ITS RESECTION | 2011 |
|
RU2454176C1 |
| METHOD FOR PREDICTION OF RISK OF PROGRESSION OF METASTATIC COLORECTAL CANCER AFTER ANTI-EGFR THERAPY | 2024 |
|
RU2820402C1 |
| METHOD FOR PREDICTION OF OVERALL SURVIVAL IN PATIENTS SUFFERING FROM LIVER METASTASES OF COLORECTAL CANCER FOLLOWING HEPATIC RESECTION | 2013 |
|
RU2530608C1 |
