FIELD: medicine.
SUBSTANCE: laboratory animals (mice) receive intravenous allogeneic transplantation of multipotent stromal cells (MMSC) and hemopoietic stem cells (HSC) obtained from the laboratory animal placenta chorion 20 minutes after irradiation. At that, MMSC are administered at a dose of 6.2 million cells/kg, and HSC - at a dose of 330 thousand cells/kg.
EFFECT: increased activation of spleen lymphoid tissue regeneration compared to other doses of stem cells introduction.
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| Title | Year | Author | Number |
|---|---|---|---|
| METHOD OF ACTIVATING ERYTHROPOESIS OF LABORATORY ANIMALS AFTER RADIATION EXPOSURE | 2017 |
|
RU2654228C1 |
| METHOD FOR RECOVERING BIOCHEMICAL PARAMETERS OF PERIPHERAL BLOOD OF LABORATORY ANIMALS WITH HEPATIC CIRRHOSIS | 2019 |
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| METHOD FOR RECOVERING BIOCHEMICAL INDICES OF PERIPHERAL BLOOD OF LABORATORY ANIMALS WITH TOXIC HEPATITIS | 2020 |
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| METHOD OF THE TREATMENT OF LIVER FIBROSIS BY ALLOGENEIC TRANSPLANTATION OF MULTIPOTENT MESENCHYMAL STROMAL CELLS (MMSC) OF LABORATORY ANIMALS | 2022 |
|
RU2802673C1 |
| METHOD OF RECOVERING SPLEEN AFTER RADIATION LOAD | 2013 |
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RU2551937C1 |
| METHOD FOR ACTIVATING MYELOID TISSUE REGENERATION IN OLD LABORATORY ANIMALS | 2013 |
|
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| METHOD FOR INCREASING REGENERATION ACTIVITY OF RAT'S INTESTINAL EPITHELIUM FOLLOWING RADIATION EXPOSURE | 2013 |
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| METHOD FOR ACCELERATING POST-RADIATION RECOVERY OF SPLEEN IN LABORATORY ANIMALS | 2021 |
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| METHOD FOR PREVENTION OF ACUTE GRAFT-VERSUS-HOST DISEASE FOLLOWING MARROW ALLOGRAFTING | 2010 |
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| METHOD OF RESTORING MYELOID TISSUE OF OLD LABORATORY ANIMALS AFTER INFLUENCE OF IONISING IRRADIATION | 2008 |
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RU2394585C1 |
