FIELD: chemistry.
SUBSTANCE: invention relates to the method for obtaining aromatic acetylene ketones of the general formula
,
wherein Ar is an aromatic radical, R is C3H7, i-C3H7, C15H31, which find a diverse application in the synthesis of various heterocyclic compounds. The method includes the interaction of tetra (phenylethynyl) tin with acid chloride of carboxylic acid in an ethereal solvent, wherein dioxane is used as the ethereal solvent, n-butanolate, 2-methylpropanoate or hexadecanolide are used as the acid chloride of carboxylic acids, the interaction is carried out in the presence of 10 mole % of zinc chloride relative to the acid chloride of carboxylic acid, used as catalyst, at a temperature of 50-60°C under stirring for 10-30 minutes in accordance with the scheme:
.
EFFECT: method allows to obtain target products using a simple technology.
1 tbl, 7 ex
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Authors
Dates
2018-01-22—Published
2017-04-13—Filed