NEW SEMI-SYNTHETIC EREMOMYCINE DERIVATIVE AND ITS APPLICATION Russian patent published in 2018 - IPC C07K9/00 A61K38/14 A61P31/04 

Abstract RU 2641912 C1

FIELD: pharmacology.

SUBSTANCE: invention relates to a new semi-synthetic derivative of glycopeptide eremomycine antibiotic, which is eremomycine tetramethylenimide of formula

, and its pharmaceutically acceptable salts. A method for production of eremomycine tetramethylenimide of formula 2, its pharmaceutical compositions and their use for treatment of mammalian infections caused by gram-positive bacteria, including insensitive or low-sensitive to other antibiotics.

EFFECT: compound efficiency increase.

6 cl, 4 tbl, 6 ex

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RU 2 641 912 C1

Authors

Olsufeva Evgeniya Nikolaevna

Shchekotikhin Andrej Egorovich

Bychkova Elena Nikolaevna

Zbarskij Viktor Borisovich

Mirchink Elena Pavlovna

Isakova Elena Borisovna

Chernobrovkin Mikhail Gennadevich

Shobolov Dmitrij Lvovich

Dates

2018-01-23Published

2016-11-02Filed