FIELD: pharmaceutical industry.
SUBSTANCE: invention relates to a pharmaceutically acceptable salt of eremomycin amide, containing an optionally substituted guanidine residue connected by an alkyl linker to the nitrogen atom of the C-terminal group of eremomycin amide, and hydrates thereof of formula:
,
where R is independently hydrogen, alkyl or optionally substituted arylalkyl; m regardless of 2 to 3. These compounds can be used to treat bacterial infectious diseases caused by strains of gram-positive pathogens.
EFFECT: creation of more effective antibacterial agents based on eremomycin.
4 cl, 1 dwg, 4 tbl, 18 ex
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