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IPC

C07D487/04(2006-01-01)

A61K31/4196(2006-01-01)

A61P31/06(2006-01-01)

(21) (22)

Application

2022112004, 2022-05-04

(24)

Start date

2022-05-04

(22)

Actual filing date

2022-05-04

(45)

Published

2023-08-24

(72)

Inventor

Charushin Valerii NikolaevichIshmetova Rashida IrshotovnaIgnatenko Nina KonstantinovnaKorotina Anna VladimirovnaBeliaev Danila VladimirovichVakhrusheva Diana VladimirovnaTolshchina Svetlana GennadevnaEremeeva Natalia IvanovnaKrasnoborova Svetlana IurevnaRusinov Gennadii Leonidovich

(73)

Holder

Federalnoe Gosudarstvennoe Biudzhetnoe Uchrezhdenie Nauki Institut Organicheskogo Sinteza Im. I.Ia. Postovskogo Uralskogo Otdeleniia Rossiiskoi Akademii NaukFederalnoe Gosudarstvennoe Biudzhetnoe Uchrezhdenie Meditsinskii Issledovatelskii Tsentr Ftiziopulmonologii I Infektsionnykh Zabolevanii" Ministerstva Zdravookhraneniia Rossiiskoi Federatsii

ANTI-TUBERCULOSIS AGENTS BEING 3,7-DISUBSTITUTED [1,2,4]TRIAZOLO[1,5-b][1,2,4,5]TETRAZINES Russian patent published in 2023 - IPC C07D487/04 A61K31/4196 A61P31/06

Abstract RU 2802300 C1

FIELD: pharmaceutical chemistry.

SUBSTANCE: group of inventions includes 3,7-disubstituted [1,2,4]triazolo[1,5-b][1,2,4,5]tetrazines of formula I–VI and a method of their preparation. Where R = 2-pyridyl, R¹ = 3,5-dimethylpyrazol-1-yl (I); R = pyrazole, R¹ = methoxy (II); R = 1,2,4-triazol-1-yl, R¹ = methoxy (III); R = 1,2,4-triazol-1-yl, R¹ = ethoxy (IV); R=3-nitrophenyl, R¹ = isopropoxy (V); R = methyl, R¹ = ONa (VI).

EFFECT: 3,7-disubstituted [1,2,4]triazolo[1,5-b][1,2,4,5]tetrazines of formula I–VI having antibacterial activity.

2 cl, 1 tbl, 6 ex

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RU 2 802 300 C1

Authors

Charushin Valerii Nikolaevich

Ishmetova Rashida Irshotovna

Ignatenko Nina Konstantinovna

Korotina Anna Vladimirovna

Beliaev Danila Vladimirovich

Vakhrusheva Diana Vladimirovna

Tolshchina Svetlana Gennadevna

Eremeeva Natalia Ivanovna

Krasnoborova Svetlana Iurevna

Rusinov Gennadii Leonidovich

Dates

2023-08-24—Published

2022-05-04—Filed