FIELD: medicine.
SUBSTANCE: modelling of endothelial dysfunction is performed in the experiment by intraperi toneal introduction of NO L-nitro-arginine-methyl ester synthesis blocker to a laboratory animal - rat - for 7 days, daily at a dose of 25 mg/kg of animal body weight. At that simultaneous correction of endothelial dysfunction is performed by intragastrical ademetionine introduction via probe at a dose of 150 mg/kg and taurine introduction an hour after at a dose of 260 mg/kg once a day.
EFFECT: invention provides correction of endothelial dysfunction due to the effective action of a combination of two drugs on vascular endothelium functioning.
2 dwg, 1 ex
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