METHOD FOR PREDICTING BREAST CANCER RECURRENT DURING ENDOCRINE TREATMENT Russian patent published in 2018 - IPC C12Q1/68 G06F19/10 

Abstract RU 2654587 C2

FIELD: biochemistry.

SUBSTANCE: invention relates to biochemistry, in particular to a method for predicting the breast cancer outcome in an estrogen-receptor-positive and HER2-negative tumor in a patient with breast cancer, which involves determining in the tumor sample of the patient the expression level of RNA genes UBE2C, BIRC5, DHCR7, STC2, AZGP1, RBBP8, IL6ST and MGP or genes UBE2C, RACGAP1, DHCR7, STC2, AZGP1, RBBP8, IL6ST and MGP, mathematical combination of values of expression levels, where a higher composite indicator indicates a worse prognosis for said patient compared to a lower composite indicator.

EFFECT: invention allows to effectively predict the breast cancer outcome.

10 cl, 3 dwg, 10 tbl

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RU 2 654 587 C2

Authors

Dartmann Marajke

Feder Inke Zabine

Germann Matias

Khennig Gvido

Veber Karsten

Fon Terne Kristian

Kronenvett Ralf

Petri Kristof

Dates

2018-05-21Published

2011-03-29Filed