6-(3,5-DIPHENYL-1,3,4-THIADIAZOL-2(3H)-YLIDEN)-2,4-DIPHENYL-4H-1,3,4-THIADIAZIN-5-ONE AND METHOD OF ITS PRODUCTION Russian patent published in 2018 - IPC C07D417/04 A61P31/04 

Abstract RU 2659574 C2

FIELD: chemistry.

SUBSTANCE: invention relates to organic and medical chemistry, namely to 6-(3,5-Diphenyl-1,3,4-thiadiazol-2(3H)-ylidene)-2,4-diphenyl-4H-1,3,4-thiadiazin-5-one of the formula I. Invention also relates to a process for its preparation. Process is carried out by reacting thiadiazole with sodium hydroxide followed by oxidative cyclisation with air oxygen. And thiadiazole is boiled with sodium hydroxide in a water-alcohol medium with a reflux condenser, then the reaction mass is kept in air at room temperature, followed by isolation of the desired product. .

EFFECT: technical result is preparation of a new chemical compound that can be used in medicine as a potential antimicrobial agent.

3 cl, 1 dwg, 2 ex, 4 tbl

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RU 2 659 574 C2

Authors

Koshevenko Anastasiya Sergeevna

Yuskovets Valerij Nikolaevich

Yakovlev Igor Pavlovich

Starova Galina Leonidovna

Ananeva Elena Petrovna

Ksenofontova Galina Vladimirovna

Dates

2018-07-05Published

2016-12-27Filed