FIELD: chemistry.
SUBSTANCE: invention relates to a method of producing a compound of general formula I, where R=Ph. Disclosed method is carried out by reacting N'-phenylbenzothiohydrazide with maleic anhydride in catalysis with 1,4-diazabicyclo[2.2.2]octane in molar ratio 2.1:4.1:0.8, respectively, in ethyl acetate for 24 hours at ambient temperature, the end product is separated from ethyl acetate, for which ethyl acetate is distilled off, 2 parts of chloroform and 5 parts of hexane are successively added to the residue, the obtained precipitate of the end product is filtered and dried.
EFFECT: obtaining a compound with high output, which can be used in medicine, for example, as an antihyperglycemic agent.
1 cl, 1 tbl, 2 ex
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Authors
Dates
2024-11-28—Published
2023-12-20—Filed