PHARMACEUTICAL ANTITUMOR COMPOSITION BASED ON SALT OLIVOMICINE DERIVATIVE Russian patent published in 2018 - IPC A61K31/704 A61P35/00 

Abstract RU 2662087 C1

FIELD: pharmaceuticals.

SUBSTANCE: present invention relates to chemical and pharmaceutical industries and is a pharmaceutical antitumor composition based on salt of N,N-dimethylaminoethylamide 1’-des-(2,3-dihydroxy-n-butyroyl)-1’-carboxyiolimicin A, selected from the group of methanesulfonate, hydrochloride, citrate and fumarate of N,N-dimethylaminoethylamide 1’-des-(2,3-dihydroxy-n-butyroyl)-1’-carboxyiolimicin A. Invention allows obtaining a pharmaceutical composition that is more stable when stored with an appropriate or greater antitumor activity than a free base N,N-dimethylaminoethylamide 1’-des-(2,3-dihydroxy-n-butyroyl)-1’-carboxyiolimicin A.

EFFECT: pharmaceutical antitumor composition is proposed.

7 cl, 7 dwg, 6 tbl, 6 ex

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RU 2 662 087 C1

Authors

Tevyashova Anna Nikolaevna

Shchekotikhin Andrej Egorovich

Shtil Aleksandr Albertovich

Bychkova Elena Nikolaevna

Treshchalin Ivan Dmitrievich

Dates

2018-07-23Published

2017-10-12Filed