FIELD: medicine.
SUBSTANCE: invention relates to medicine. DNA of buccal epithelium is sampled, polymorphism of receptor genes activated by peroxisomal proliferators: PPARA, PPARG and PPARGC1A. If observing variant homozygous or heterozygous genotypes of PPARA gene (rs4253778), PPARG gene (rs1801282) and PPARGC1A gene (rs8192678), a risk of developing essential hypertension associated with obesity in men. Invention provides reliable prediction of the risk of developing essential hypertension associated with obesity in men by using a combination of genetic variants of loci as diagnostic criteria rs4253778 PPARA, rs1801282 PPARG and rs8192678 PPARGC1A.
EFFECT: what is presented is a method for prediction of men's risk of essential hypertension associated with obesity.
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Authors
Dates
2019-07-03—Published
2018-12-04—Filed