PROCESS FOR PREPARATION OF N-[(3-AMINOOXETAN-3-YL)METHYL]-2-(1,1-DIOXO-3,5-DIHYDRO-1,4-BENZOTHIAZEPINE-4-YL)-6-METHYL-QUINAZOLINE-4-AMINE Russian patent published in 2018 - IPC C07D417/14 C07D305/06

Abstract RU 2664643 C2

FIELD: chemistry.

SUBSTANCE: invention relates to a novel process for the preparation of a compound of formula (I). Method makes it possible to obtain the product in good yield and purity. .

EFFECT: new method has been developed for the preparation of a compound of formula (I) which is useful for the prevention and treatment of an infection caused by a respiratory syncytial virus (RSV) in a mammal or human.

21 cl, 1 tbl, 13 ex

Similar patents RU2664643C2

Title	Year	Author	Number
METHODS FOR SYNTHESIS OF 3-(4-(2,4-DIFLUOROBENZYLOXY)-3-BROMO-6-METHYL-2-OXOPYRIDIN-1 (2H)-YL)-N-4-DIMETHYLBENZAMIDE	2007	D'Juksherir Dehniel Mao Majkl Vonder Ehmbs Richard Jalamanchili Gopichand Vajd'Janatan Radzhappa Chekal Brajan Klemm Dzhordzh Vanderrost Ronal'D G'Jurink Rehndi	RU2411236C1
1,3,4-OXADIAZOLE SULPHAMIDE DERIVATIVES AS HISTONE DEACETYLASE 6 INHIBITOR AND PHARMACEUTICAL COMPOSITION CONTAINING THEM	2016	Lee, Jaekwang Han, Younghue Kim, Yuntae Min, Jaeki Bae, Miseon Kim, Dohoon Jin, Seokmin Kyung, Jangbeen	RU2695227C1
METHODS FOR PREPARING DERIVATIVES OF 1-[2-(BENZIMIDAZOL-1-YL)QUINOLIN-8-YL]PIPERIDIN-4-YLAMINE	2004	Tom Norma Zhaklin Ripin Dejvid Kharold Braun Kastal'Di Majkl Dzhejms	RU2323214C2
TARTRATE 3-((1R,3R)-1-(2,6-DIFLUORINE-4-((1-(3- FLUOROPROPYL)AZETIDINE-3-YL)AMINO)PHENYL)-3-METHYL-1,3,4,9-TETRAHYDRO-2H-PYRIDO[3,4-b]INDOLE-2-YL)-2,2-DIFLUOROPROPANE-1-OL, ITS SOLID FORMS, METHOD OF ITS PREPARATION AND THEIR APPLICATION	2019	Chunk, Chol Keun Syuj, Tsze Iding, Khans Klagg, Kajl Delzil, Majkl Fettes, Alek Gosselin, Frensis Lim, Ngiap-Kie Makklori, Endryu Chzhan, Khajmin Chakravarti, Paroma Nagapudi, Kartik Robinson, Sara	RU2809220C2
HETEROCYCLIC COMPOUND	2019	Ono, Koji Ito, Masahiro Tanaka, Toshio Asano, Moriteru Hirayama, Takaharu Fujimoto, Jun Sakauchi, Nobuki Hirata, Yasuhiro Toita, Akinori Morishita, Nao Kokubo, Hironori Imaeda, Yasuhiro Maezaki, Hironobu Cary, Douglas Robert Mizojiri, Ryo Cho, Nobuo Banno, Hiroshi Tokuhara, Hidekazu Arikawa, Yasuyoshi	RU2815003C2
METHOD OF PRODUCING 3-[5-[4-(CYCLOPENTYLOXY)-2-HYDROXYBENZOYL]-2-[(3-OXO-2-SUBSTITUTED-2, 3-DIHYDRO-1, 2-BENZISOXAZOL-6-YL)METHOXY]PHENYL]PROPIONIC ACID ESTER AND INTERMEDIATE PRODUCT FOR SAID METHOD	2007	Jonezava Kendzi Takamatsu Tamotsu Aoki Naokatu Khasimoto Tomokhiro Takebajasi Masakhiro Suzuki Josiaki Oonisi Judzi	RU2434002C2
(6S,9AS)-N-BENZYL-6-[(4-HYDROXYPHENYL)METHYL]-4,7-DIOXO-8-({6-[3-(PIPERAZIN-1-YL)AZETHYDIN-1-YL]PYRIDINE-2-YL}METHYL)-2-(PROP-2-EN-1-YL)-OCTAHYDRO-1H-PYRASINO[2,1-C][1,2,4]TRIAZINE-1-CARBOXAMIDE COMPOUND	2014	Inoue Satosi Yamamoto Yudzi Iso Kentaro	RU2669805C2
METHOD FOR PRODUCING 2-[(3R)-3-METHYLMORPHOLIN-4-YL]-4-(1-METHYL-1H-PYRAZOL-5-YL)-8-(1H-PYRAZOL-5-YL)-1,7-NAFTHYRIDINE	2019	Platzek Johannes Rubenbauer Philipp Van Der Haas Hendricus Nicolaas Sebastiaan Hoogeveen Sonja Elisabeth Van Oers Matthijs Cornelis Maria Gieling Reinerus Gerardus Dekker Jeroen Alexander	RU2802512C2
SUBSTITUTED METHYL(2-{4-[3-(3-METHANESULFONYLAMINO-2-FLUORO-5-CHLORO-PHENYL)-1H-PYRAZOL-4-YL]PYRIMIDIN-2-YLAMINO}ETHYL) CARBAMATES, PROCESS FOR THEIR PREPARATION AND APPLICATION	2016	Ivashchenko Aleksandr Vasilevich Ignatev Vasilij Gennadevich Repik Aleksej Evgenevich Shafeev Mikhail Ajratovich	RU2615986C1
1,3,4-OXADIAZOLE SULPHONAMIDE DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS 6 AND PHARMACEUTICAL COMPOSITION CONTAINING THEREOF	2016	Lee, Jaekwang Han, Younghue Kim, Yuntae Choi, Daekyu Min, Jaeki Bae, Miseon Yang, Hyunmo Kim, Dohoon	RU2697665C1

RU 2 664 643 C2

Authors

Chen Tszyunli

Zhen I

She Tszin

Van Lin

Yuj Tszyankhua

Chzhan Gotsaj

Dates

2018-08-21—Published

2015-01-21—Filed