FIELD: medicine.
SUBSTANCE: invention relates to medicine and relates to organ transplantation. To this end, an organ is exposed to exogenous stem cells, the stem cells being non-embryonic non-germ cells that express telomerase, have a normal karyotype, are not tumorigenic. Stem cells were subjected to at least 10-40 cell divisions in a culture prior to exposure of the organ to said cells, and wherein the organ is exposed to the stem cells prior to transplantation to a recipient.
EFFECT: invention provides a beneficial effect on the organ with respect to the proliferation of T cells, ischemic reperfusion by treating the organ with stem cells prior to transplantation to the recipient.
18 cl, 2 tbl, 7 dwg
| Title | Year | Author | Number |
|---|---|---|---|
| IMPROVEMENT OF ORGANS FOR TRANSPLANTATION | 2014 |
|
RU2778304C2 |
| METHODS OF DERIVING DIFFERENTIATED CELLS FROM STEM CELLS | 2009 |
|
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| METHODS FOR PRODUCING TISSUES | 2013 |
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| METHOD OF TREATING IMMUNE DYSFUNCTION, SUCH AS GRAFT-VERSUS-HOST OR HOST-VERSUS-GRAFT DISEASE | 2006 |
|
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| METHODS OF OBTAINMENT AND APPLICATION OF MULTIPOTENT CELL POPULATIONS | 2008 |
|
RU2535365C2 |
| OBTAINING PLURIPOTENT CELLS DE NOVO | 2013 |
|
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| HUTC MODULATION OF PRO-INFLAMMATORY MEDIATORS OF LUNG AND PULMONARY DISEASES AND DISORDERS | 2013 |
|
RU2668389C2 |
| METHOD OF USING STEM CELLS IN TISSUE REPLACEMENT THERAPY | 2009 |
|
RU2422514C1 |
| METHOD FOR ISOLATION OF PLURIPOTENT STEM CELLS FROM UMBILICAL BLOOD EXPRESSING ZNF281 | 2010 |
|
RU2511417C2 |
| DIFFERENTIATION OF PLURIPOTENT STEM CELLS | 2011 |
|
RU2673946C1 |
