FIELD: medicine.
SUBSTANCE: group of inventions refers to the field of medicine, in particular to a composition comprising an immunogenic preparation of cells of a dead Leptospira bacterium in a solution of 10, 20 or 50 mmol/L of citric acid. It also relates to a vaccine for protecting animals from infection with the bacterium Leptospira, where the vaccine contains the composition, and to the use of 10, 20 or 50 mmol/L citric acid to stabilize the immunogenic preparation of the dead Leptospira bacterium in a liquid carrier by dissolving the citric acid in the carrier.
EFFECT: group of inventions provides the creation of a vaccine against leptospirosis, which remains effective after three months of storage at 37 °C.
8 cl, 11 tbl, 4 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR PREVENTIVE TREATMENT OF PIGS | 2017 |
|
RU2780233C2 |
| LEPTOSPIRA WITH INCREASED ANTIGENIC MASS | 2013 |
|
RU2679040C2 |
| VACCINE AGAINST ANIMAL LEPTOSPIROSIS | 1990 |
|
RU2030915C1 |
| INACTIVATED COMBINED VACCINE AGAINST CATTLE INFECTIOUS RHINOTRACHEITIS, VIRUS DIARRHOEA AND LEPTOSPIROSIS | 2009 |
|
RU2395297C1 |
| INACTIVATED COMBINED VACCINE AGAINST CATTLE INFECTIOUS RHINOTRACHEITIS, VIRUS DIARRHOEA, ROTA-, CORONAVIRUS DISEASE AND LEPTOSPIROSIS | 2009 |
|
RU2395299C1 |
| METHOD OF PRODUCING POLYVALENT VACCINE AGAINST EQUINE LEPTOSPIROSIS | 2023 |
|
RU2815538C1 |
| VACCINE AGAINST PLAGUE, ADENOVIRUS INFECTIONS, PARVOVIRUS AND CORONAVIRUS ENTERITIS, LEPTOSPIROSIS AND RABIES OF DOGS | 2013 |
|
RU2546247C2 |
| NEW MULTIVALENT VACCINE AGAINST HUMAN LEPTOSPIROSIS AND A METHOD FOR ITS PRODUCTION | 2021 |
|
RU2753972C1 |
| TEST STRAIN LEPTOSPIRA INTERROGANS OF SEROGROUP GRIPPOTYPHOSA OF SEROVAR GRIPPOTYPHOSA FOR DETECTION OF ANTIBODIES TO L. GRIPPOTYPHOSA | 2020 |
|
RU2752978C1 |
| STRAIN OF BACTERIUM LEPTOSPIRA INTERROGANS "MITRONOV" OF SERUM GROUP CANICOLA FOR PREPARING VACCINE | 2002 |
|
RU2227160C1 |
