METHOD OF PRODUCING (R)-5-(3,4-DIFLUOROPHENYL)-5-[(3-METHYL-2-OXOPYRIDINE-1(2H)-YL)METHYL]IMIDAZOLIDINE-2,4-DIONE AND AN INTERMEDIATE COMPOUND FOR SYNTHESIS THEREOF Russian patent published in 2020 - IPC C07D401/06 

Abstract RU 2735600 C2

FIELD: chemistry.

SUBSTANCE: invention relates to a method of producing (R)-5-(3,4-difluorophenyl)-5-[(3-methyl-2-oxopyridine-1(2H)-yl)methyl]imidazolidine-2,4-dione

including: (a) a step for separating an isomer represented by following formula (2)

from a mixture of isomers of formula (1); and

(b) a step for removing the mentyloxycarbonyl group of the compound, represented by formula (2) recovered at step (a), to obtain (R)-5-(3,4-difluorophenyl)-5-[(3-methyl-2-oxopyridine-1(2H)-yl)methyl]imidazolidine-2,4-dione.

EFFECT: invention discloses a method of producing (R)-5-(3,4-difluorophenyl)-5-[(3-methyl-2-oxopyridine-1(2H)-yl)methyl]imidazolidine-2,4-dione and an intermediate compound for obtaining.

3 cl, 2 dwg, 1 tbl, 4 ex

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RU 2 735 600 C2

Authors

Sumikawa Yoshitake

Kamei Noriyuki

Todo Shingo

Dates

2020-11-05Published

2017-09-21Filed