ANALOGUE OF BENZOFURANE AS NS4B INHIBITOR Russian patent published in 2018 - IPC C07D405/06 A61K31/343 A61K31/496 A61K31/5513 A61P31/12 

Abstract RU 2672257 C2

FIELD: chemistry.

SUBSTANCE: invention relates to the field of organic chemistry, specifically to a heterocyclic compound of formula (I) or a pharmaceutically acceptable salt thereof, where the component is or L1 represents -C(=O)-; L2 is a bond; m is selected from the group consisting of 1, 2, 3, and 4; R3 is each of R11, R12 is independently selected from the group consisting of F, Cl, Br, I, CN, C1-10-alkyl and C3-10-cycloalkyl, C1-10-alkyl and C3-10-cycloalkyl optionally substituted with zero, one, two or three R01; R01 selected from the group consisting of F, Cl, Br and I.

.

EFFECT: new benzofuran derivative has been obtained that is used as an NS4B inhibitor and is useful in treating the disease caused by the hepatitis C virus.

5 cl, 1 tbl, 68 ex

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RU 2 672 257 C2

Authors

Zhang Yang

Fu Zhifei

Wang Jianfei

Li Jian

Chen Shuhui

Wei Yuquan

Yu Luoting

Tao Xin

Dates

2018-11-13Published

2015-09-23Filed