METHOD FOR CONTROL OVER PROCESS OF PERIPHERAL NERVE REGENERATION AFTER INJURY IN EXPERIMENT Russian patent published in 2018 - IPC G01N33/48 

FIELD: medicine.

SUBSTANCE: invention relates to medicine and can be used in neurohistology to monitor the dynamics of regeneration after an injury to peripheral nerves. For this purpose, a sample of blood serum of an animal (rat) with a peripheral nerve injury is taken for the study on the 90^th, 150^th, 300^th day after the injury, the study is carried out using the method of IR spectroscopy, for this, the sample of blood serum is pre-dried, the dry residue is crushed and suspended in petroleum jelly, the IR spectra are taken in the region of 1,200–1,000 cm^-1, then the height of the peaks of the absorption bands with maximums at 1165, 1125, 1070, 1025 cm^-1 is determined, then the value of the ratio of the height of the peak with a maximum at 1,165 cm^-1 to the height of the peak with a maximum at 1,125 cm^-1 is calculated (PARAMETER 1) and the value of the ratio of the height of the peak with a maximum at 1,070 cm^-1 to the height of the peak with a maximum at 1,025 cm^-1 (PARAMETER 2) is calculated, and if the value of PARAMETER 1 on the 90^th day is >1.06, on the 150^th day is >1.11, on the 300^th day is >0.88 and the value of PARAMETER 2 on the 90^th day is <0.76, on 150^th day is <0.63, on the 300^th day is <0.73, a conclusion is made about the positive dynamics of the regeneration of the peripheral nerve after an injury.

EFFECT: invention provides a quick accurate and low-cost control method that can be used in clinical practice.

1 cl, 4 ex