METHOD FOR PREDICTING COURSE OF REPARATIVE PROCESS OF LAPAROTOMY WOUND IN CASE OF ACUTE PERITONITIS Russian patent published in 2019 - IPC G01N33/49 

FIELD: medicine.

SUBSTANCE: invention relates to the field of medicine, namely to surgery, and is intended to predict the course of the reparative process of a laparotomy wound in acute peritonitis. Patient immediately after surgery and one day after it determines the severity of endogenous intoxication by the level of medium-weight molecules, the activity of oxidative stress by the level of malondialdehyde and the microcirculation index. Based on the data obtained, an index is predicted for predicting the course of the reparative process of a laparotomy wound in acute peritonitis using the formula:

where IPRP is the index for predicting the course of the reparative process of a laparotomic wound in acute peritonitis, AWM_n – the level of average weight molecules in the blood is normal, AWM₁ – the level of molecules of average mass in the blood after surgery, AWM₂ – the level of molecules of average mass in the blood in one day after the operation, MDA_n – the level of malondialdehyde in the blood is normal, MDA₁ – the level of malondialdehyde in the blood after surgery, MDA₂ – the level of malondialdehyde in the blood after one day after surgery, IM_n – the index of skin microcirculation is normal, IM₁ – an indicator of skin microcirculation after surgery, IM₂ – an indicator of microcirculation of the skin one day after surgery. When the value of IPRP is less than 13.0 predict a low probability of violation of the reparative process of postoperative wounds. When the value of IPRP is from 13.1 to 16.0 predict the average degree of probability of violation of the reparative process of postoperative wounds. When the value of IPRP is from 16.1 and more predict a high degree of probability of violation of the reparative process of postoperative wounds.

EFFECT: use of the invention provides an effective prediction of the course of the reparative process of a laparotomic wound in acute peritonitis.

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