ERYTHROFERRONE AND ERFE POLYPEPTIDES AND METHODS FOR REGULATING IRON METABOLISM Russian patent published in 2019 - IPC C07K14/525 C07K7/08 C12P21/02 C07K16/18 C12N5/12 G01N33/68 A61K38/19 A61P3/12 

Abstract RU 2684216 C2

FIELD: biotechnology.

SUBSTANCE: invention relates to the field of biotechnology, specifically to modulating the amount of hepcidin, and can be applied in medicine for treatment of diseases associated with the metabolism of iron in a subject. This method of treatment involves administering to a subject a composition comprising (I) an antibody that specifically recognizes an erythroferrone polypeptide or a fragment thereof, and (II) a pharmaceutically acceptable carrier or diluent.

EFFECT: invention is effective in hemochromatosis or disorders associated with abnormally low levels of hepcidin.

4 cl, 12 dwg

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RU 2 684 216 C2

Authors

Ganz Tomas

Nemet Elizabeta

Kautts Leon

Dates

2019-04-04Published

2013-10-31Filed