FIELD: biotechnology.
SUBSTANCE: invention relates to the field of biotechnology, specifically to modulating the amount of hepcidin, and can be applied in medicine for treatment of diseases associated with the metabolism of iron in a subject. This method of treatment involves administering to a subject a composition comprising (I) an antibody that specifically recognizes an erythroferrone polypeptide or a fragment thereof, and (II) a pharmaceutically acceptable carrier or diluent.
EFFECT: invention is effective in hemochromatosis or disorders associated with abnormally low levels of hepcidin.
4 cl, 12 dwg
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Authors
Dates
2019-04-04—Published
2013-10-31—Filed