CHROMINE DERIVATIVE AS DOPAMINE D3 RECEPTOR ANTAGONIST FOR APPLICATION IN TREATING AUTISM SPECTRUM DISORDER Russian patent published in 2019 - IPC A61K31/496 A61P25/18 A61P25/28 A61K45/00 

Abstract RU 2686110 C1

FIELD: chemical-pharmaceutical industry.

SUBSTANCE: group of inventions relates to use of a chromone derivative. Disclosed are: use of N-(3-{4-[4-(8-oxo-8H-[1,3]dioxolo[4,5-g]chromene-7-yl)-butyl]-piperazin-1-yl}-phenyl)methanesulphonamide or a pharmaceutically acceptable salt thereof as a medicament for treating a social interaction deficiency associated with an autism spectrum disorder, and a pharmaceutical composition of the same purpose based thereon.

EFFECT: technical result is a compound which represents a dopamine D3 receptor antagonist, eliminates the deficiency of social interactions caused by the prenatal action of sodium valproate.

4 cl, 1 dwg, 2 ex

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RU 2 686 110 C1

Authors

Okler Anes

Mozer Pol

Sokoloff Per

Dates

2019-04-24Published

2014-12-12Filed