FIELD: immunology.
SUBSTANCE: disclosed are a humanised antibody or its antigen-binding fragment, as well as antibodies or antigen-binding fragments thereof, which specifically bind to human H7CR. Also disclosed is a pharmaceutical composition, a method of treating a disease associated with H7CR expression, and a method for enhancing the immune response. What is also described is a method for preventive treatment and a method for diagnosing a disease associated with H7CR expression.
EFFECT: present invention can find further application in therapy of various conditions, in particular for treating and diagnosing malignant tumors.
35 cl, 23 dwg, 11 tbl, 8 ex
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