POWDER CONTAINING DEFERASIROX AND METHOD OF PREPARATION THEREOF Russian patent published in 2019 - IPC A61K31/41 A61K47/26 A61K9/00 A61K9/14 

FIELD: medicine; pharmaceuticals.

SUBSTANCE: invention refers to a pharmaceutical composition for treating iron overload in powder form containing 25 wt. % to 45 wt. % of combination of lactose and sucrose with respect to total weight of powder and containing as an active ingredient from 35 wt. % to 40 wt. % of the compound represented by formula 1, or its pharmaceutically acceptable salt and from 0.2 wt. % to 10 wt. % of sodium lauryl sulphate with respect to total weight of powder. Invention also relates to a method for preparing a pharmaceutical composition in powder form.

[Formula 1].

EFFECT: technical result: obtaining a pharmaceutical composition in powder form, containing deferasirox as an active ingredient and low percentage content of additives, which can be taken without suspension in the aqueous phase, in addition, the obtained pharmaceutical composition exhibits high rate of dissolution.

12 cl, 7 dwg, 10 tbl, 7 ex