METHOD FOR PREDICTING A CLINICAL COURSE OF EARLY NEUROSYPHILIS IN HIV-INFECTED PATIENTS Russian patent published in 2019 - IPC G01N33/48 

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely venerology, and can be used to predict a clinical course of early neurosyphilis in an HIV-infected patient. That is ensured by determining clinical form of neurosyphilis, availability of antiretroviral therapy, micro-precipitation reaction (MPR) and determining the titre value MPR blood. Grading and numerical values are established to detect risk factors, after which prognostic coefficients F₁, F₂ and F₃ by formulas. At maximum value F₁ regredient version is predicted, with maximum value F₂ – stationary version, and at maximum value F₃ – progredient clinical version of early neurosyphilis.

EFFECT: method enables providing more effective and targeted preventive and therapeutic measures in the groups of patients with a high risk of the re-competitive and stationary versions of early neurosyphilis due to accuracy up to 98 % of the individual prognosis of developing the clinical course of early neurosyphilis in the HIV-infected patient in nearest 5-year period after the diagnosis.

1 cl, 3 ex