MICROSTRUCTURE FOR TRANSDERMAL ADMINISTRATION AND A METHOD FOR PRODUCTION THEREOF Russian patent published in 2019 - IPC A61M37/00 B29C39/02 B81C1/00 C08L101/16 C09J201/00 

Abstract RU 2701361 C1

FIELD: technological processes.

SUBSTANCE: invention relates to a microstructure comprising a biocompatible polymer or adhesive and a method for production thereof. Microstructure contains a biocompatible polymer or adhesive, where the aspect ratio (w:h) including the diameter (w) of the lower surface of the microstructure and the height (h) of the microstructure ranges from 1:5 to 1:1.5, and the value of the angle of the distal tip is from 10° up to 40° and where multiple microstructures are arranged in the form of hexagon. In particular, microstructures from B-type to D-type according to the invention minimize resistance to penetration caused by skin elasticity, when combined with skin, thus increasing the penetration rate of structures (60 % or higher) and rate of absorption of useful ingredients into skin. Besides, microstructure of D-type according to invention maximally increases mechanical strength of structure due to use of triple structure and due to it can easily penetrate into skin. In case multiple microstructures have hexagonal arrangement, uniformly distributed pressure can be transferred to all microstructures on skin.

EFFECT: invention optimizes the aspect ratio in accordance with the type of each of the microstructures, thereby providing the tip angle and the diameter range optimal for penetration through the skin.

18 cl, 27 dwg, 4 tbl

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RU 2 701 361 C1

Authors

Kim, Dzhe Soo

Kvon, Soon Chan

Park, San Dzhin

Dates

2019-09-27Published

2016-12-22Filed