FIELD: medicine.
SUBSTANCE: invention relates to use of 5-methyl-7-(3-nitro-[1,2,4]triazol-1-yl)-[1,2,4]triazolo[1,5-a]pyrimidine of formula 1 as an anti-tuberculosis substance with activity on a multiple drug resistance agent.
EFFECT: disclosed is use of 5-methyl-7-(3-nitro-[1,2,4]triazol-1-yl)-[1,2,4]triazolo[1,5-a]pyrimidine for treating tuberculosis with multiple drug resistance.
1 cl, 5 dwg, 4 tbl, 4 ex
| Title | Year | Author | Number |
|---|---|---|---|
| COMPOUND OF 8-(4-METHYL-4H-1,2,4-TRIAZOL-3-YL)-6-(METHYLSULPHONYL)-2-(5-NITRO-2-FUROYL)-2,6-DIAZASPIRO[3.4]OCTANE, HAVING ANTI-TUBERCULOSIS ACTIVITY AGAINST MULTIDRUG-RESISTANT TUBERCULOSIS AGENT, AND METHOD FOR PRODUCTION THEREOF | 2023 |
|
RU2825646C1 |
| ENANTIOMERS 6-ETHOXYCARBONYL-7-(THIEN-2-YL)-5-METHYL-4,7-DIGYDRO-1,2,4-TRIAZOLO[1,5-A]PYRIMIDINE AND 6-ETHOXYCARBONYL-7-PHENYL-5-METHYL-4,7-DIHYDRO-1,2,4-TRIAZOLO[1,5-A]PYRIMIDINE, WITH TUBERCULOSTATIC ACTIVITY | 2017 |
|
RU2654463C1 |
| COMPOUND 1-[(5-NITROFURAN-2-YL)CARBONYL]-2'-CYCLOHEXYL-1H,7'H-SPIRO[AZETIDINE-3,5'-FURO[3,4-D]PYRIMIDINE], HAVING ANTI-TUBERCULOSIS ACTIVITY AGAINST MULTIDRUG-RESISTANT TUBERCULOSIS AGENT, AND METHOD FOR PRODUCTION THEREOF | 2023 |
|
RU2825647C1 |
| 1-[(5-NITROFURAN-2-YL)CARBONYL]-2'-PROPYL-1H,7'H-SPIRO[AZETIDINE-3,5'-FURO[3,4-D]PYRIMIDINE], HAVING ANTI-TUBERCULOSIS ACTIVITY IN WITH RESPECT TO MULTIDRUG-RESISTANT TUBERCULOSIS AGENT, AND METHOD FOR PRODUCTION THEREOF | 2023 |
|
RU2824817C1 |
| STRAIN MYCOBACTERIUM TUBERCULOSIS 326/18/47 B-9673 FOR EVALUATION OF THE EFFECTIVENESS OF ANTI-TB DRUGS AND DISINFECTANTS | 2022 |
|
RU2785409C1 |
| 1-[(5-NITROFURAN-2-YL)CARBONYL]-2'-PHENYL-1H,7'H-SPIRO[AZETIDINE-3,5'-FURO[3,4-D]PYRIMIDINE], HAVING ANTI-TUBERCULOSIS ACTIVITY IN WITH RESPECT TO MULTIDRUG-RESISTANT TUBERCULOSIS AGENT, AND METHOD FOR PRODUCTION THEREOF | 2023 |
|
RU2824815C1 |
| DERIVATIVES OF 3,7-DIHYDRO-[1,2,4]TRIAZOLO[1,5-a]PYRIMIDINE-5-CARBOXAMIDES WITH ACTIVITY AGAINST TUBERCULOSIS, THEIR USE AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | 2024 |
|
RU2836654C1 |
| (4-(3-HYDROXYPHENYL)PIPERAZINE-1-YL)(5-NITROFURAN-2-YL)METHANON, WHICH HAS ANTITUBERCULAR ACTIVITY AGAINST THE CAUSATIVE AGENT OF MULTIDRUG-RESISTANT TUBERCULOSIS, AND THE METHOD FOR ITS PREPARATION | 2021 |
|
RU2784399C1 |
| 5-FLUORO-2-(4-ETHOXYCARBONYLDIPIPERAZINE-1-YL)-1,3-BENZOTHIAZINE-4-ONE, WHICH HAS ANTI-TUBERCULOSIS ACTIVITY | 2018 |
|
RU2663848C1 |
| SELECTIVE ANTITUBERCULOUS AGENTS REPRESENTING SUBSTITUTED 7-ARYL(HETERYL)-6-CARBETHOXY-4,7-DIHYDRO-1,2,4-TRIAZOLE[1,5-a]PYRIMIDINES OR SUBSTITUTED 7-ARYL(HETERYL)-4,7-DIHYDRO-6-NITRO-1,2,4-TRIAZOLE[1,5-a]PYRIMIDINES OR THEIR PHARMACEUTICALLY ACCEPTABLE ADDITIVE SALTS, PHARMACEUTICAL COMPOSITION THEREOF AND METHOD FOR PREPARATION OF SUBSTITUTED 7-ARYL(HETERYL)-6-CARBETHOXY-5-METHYL-4,7-DIHYDRO-1,2,4-TRIAZOLE[1,5-a]PYRIMIDINES | 2007 |
|
RU2360905C2 |
