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2 825 647

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IPC

C07D491/20(2006-01-01)

A61K31/519(2006-01-01)

A61P31/06(2006-01-01)

(21) (22)

Application

2023123605, 2023-09-11

(24)

Start date

2023-09-11

(22)

Actual filing date

2023-09-11

(45)

Published

2024-08-28

(72)

Inventor

Lukin Aleksej YurevichVinogradova Tatyana IvanovnaDogonadze Marine ZaurievnaVinogradova Lyubov VladimirovnaKomarova Kristina YurevnaDarin Dmitrij ViktorovichLavrova Anastasiya IgorevnaPostnikov Evgenij BorisovichSychev Aleksandr VladimirovichYablonskij Petr Kazimirovich

(73)

Holder

Federalnoe Gosudarstvennoe Byudzhetnoe Uchrezhdenie Nauchno-Issledovatelskij Institut Ftiziopulmonologii" Ministerstva Zdravookhraneniya Rossijskoj Federatsii

COMPOUND 1-[(5-NITROFURAN-2-YL)CARBONYL]-2'-CYCLOHEXYL-1H,7'H-SPIRO[AZETIDINE-3,5'-FURO[3,4-D]PYRIMIDINE], HAVING ANTI-TUBERCULOSIS ACTIVITY AGAINST MULTIDRUG-RESISTANT TUBERCULOSIS AGENT, AND METHOD FOR PRODUCTION THEREOF Russian patent published in 2024 - IPC C07D491/20 A61K31/519 A61P31/06

Abstract RU 2825647 C1

FIELD: pharmaceutics.

SUBSTANCE: invention relates to 1-[(5-nitrofuran-2-yl)carbonyl]-2'-cyclohexyl-1H,7'H-spiro[azetidine-3,5'-furo[3,4-d]pyrimidine] of formula 1, having anti-tuberculosis activity with respect to a multidrug-resistant agent, and a method for preparing it.

EFFECT: novel compound of formula 1 is obtained, which can be used as a substance for treating multidrug-resistant tuberculosis with low toxicity and good tolerance.

2 cl, 6 dwg, 2 tbl, 4 ex

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RU 2 825 647 C1

Authors

Lukin Aleksej Yurevich

Vinogradova Tatyana Ivanovna

Dogonadze Marine Zaurievna

Vinogradova Lyubov Vladimirovna

Komarova Kristina Yurevna

Darin Dmitrij Viktorovich

Lavrova Anastasiya Igorevna

Postnikov Evgenij Borisovich

Sychev Aleksandr Vladimirovich

Yablonskij Petr Kazimirovich

Dates

2024-08-28—Published

2023-09-11—Filed